VitroGel® offers a defined synthetic hydrogel system that closely mimics the natural ECM environment without animal or human components. This system gives researchers control over mechanical strength, functional ligands, and degradability, allowing for the creation of precise biomimetic environments tailored for various applications in drug discovery, tissue engineering, and cell therapy.
In contrast, animal-based ECMs suffer from batch-to-batch inconsistency and contain over 2,000 undefined components, highlighting the superior consistency and defined nature of the VitroGel® system for advanced biomedical research and development.
VitroGel® Hydrogel Features
Closely mimicking the natural extracellular matrix (ECM) environment, this distinct hydrogel system brings many advantages to bridge in vitro and in vivo studies through 3D cell culture and beyond.
Xeno-free, Biofunctional, and Biocompatible
100% synthetic. Animal & human origin-free hydrogel. VitroGel® supports various cell activities and safe for in vivo applications.
Stable at Room Temperature
VitroGel® is in liquid form at room temperature. Room temperature protocol/operation. No ice bucket.
Simple, Fast, and Easy-to-use
20-min protocol. Mix with cells, add medium, and incubate.
Easy Cell Harvesting
Harvest cells fast while maintaining high viability with our enzyme-free recovery solution, <20 minutes, at 37°C.
Tunable
For High Concentration Hydrogels, adjust the hydrogel stiffness from a wide range for different applications.
Reproducible
Consistency in batch-to-batch. Available for GMP process.
Transparent
Compatible with any imaging system and downstream analysis.
Injectable
Long-term injectability after gelation with no needle clogging. Ideal for xenograft, cell therapy or drug delivery applications.
Lab-Automation Friendly
Temperature stable, lab automation-friendly, easy to adapt with current liquid handling system without additional modification.
Explore VitroGel® hydrogel system and all its advantages over animal-based ECMs
Covers multiple applications of animal-based ECM and more while opening the door to clinical applications.
Supports most cell types, works with any imaging analysis, and enables downstream applications.
Ethical, sustainable, and environment-friendly (3Rs).
Two types of VitroGel® for flexibility
“Ready-To-Use” VitroGel® Hydrogels
JUST ADD CELLS- A series of user-friendly functional hydrogels optimized for different cell culture applications.
Simple, functional, and versatile alternative to animal-based ECM.
Supports a wide range of cell types and applications.
Ready to mix with cell suspension, no adjustment needed.
VitroGel® High Concentration Hydrogels
TUNABLE HYDROGELS- Building blocks for unlimited creativity and maximum flexibility. 3D cell culture your way!
Tunable hydrogels, adjustable mechanical strength from 10 to 4000 Pa.
Enables scientists to investigate the cell behaviors in response to an individual functional ligand.
Create your own ECM by mixing different functional VitroGel® hydrogels.
Learn more about VitroGel® Technology
How Does Gelation Work with
VitroGel® Hydrogels?
VitroGel® remains liquid at room temperature. The hydrogel polymerization initiates by mixing with cell culture medium, is not temperature dependent, and does not require any chemical crosslink.
Multiple Cell Culture Methods with
VitroGel® Hydrogels
The xeno-free, biofunctional VitroGel® hydrogel system is versatile for various applications such as use 3D culture, 2D Hydrogel Coating, Static Suspension Culture, Bead Formation, and Animal Injection.
Unique Injectable Properties of
VitroGel® Hydrogels
VitroGel® hydrogel system has a unique shear-thinning and rapid recovery rheological properties for easy handling such as long-term injectable status ideal for animal injection, bioprinting, droplet formation, and lab automation.
How Does Cell Harvesting/Recovery Work in
VitroGel® Hydrogels
With the VitroGel® system, harvesting cells is quick and efficient. Recover cells at neutral pH while maintaining high cell viability when using the enzyme-free VitroGel® Organoid Recovery Solution.
Performance Comparison to other 3d cell culture methods
VitroGel® provides an outstanding balance of biological functions and operating feasibility. The system closely mimic the natural extracellular matrix along with the ease of us, allowing high-throughput performance to build robust 3D cell models.
See how VitroGel® features compared to other 3D cell culture methods above.
