TheWell Bio launched VitroGel 3D for 3D cell culture and beyond

TheWell Bioscience announces new product launch: VitroGel 3D, a ready-to-use hydrogel for 3D cell culture and beyond

After years of preparation and test, TheWell Bioscience is proud to offer a distinct, ready-to-use hydrogel system-VitroGelTM 3D for three-dimensional (3D) cell culture and beyond. VitroGel 3D is an animal origin-free polysaccharide hydrogel, which closely mimics the natural extracellular matrix (ECM) environment. Compared to current marketed product, VitroGel 3D performs many advanced features. This system is room temperature stable with neutral pH. The hydrogel solution transforms into a highly cross-linked matrix structure in response to the changes of ionic strength such as directly mixing with cell culture media. The hydrogel is transparent and compatible to different imaging systems. Oxygen, nutrition and other molecules can easily move in/out the hydrogel system. Cells cultured in this system can be harvested from the hydrogel by using standard centrifuging methods. The hydrogel is also injectable for in vivo study. VitroGel 3D hydrogel system helps cells to grow more closely to their natural morphologies and behaviors, providing an excellent tool for many research fields, such as cancer research, drug development, and tissue engineering.

VitroGel 3D has been successfully used on different projects with many cell lines such as human and mouse pancreatic beta cells, insulin-secreting beta cell-derived lines, lymphocytes, Hela cells, human embryonic kidney 293 cells, human colon carcinoma cell lines (HCT–8), stem cells and much more. The results show that cells can suspend homogeneously in the hydrogel and successfully grow in the 3D structure or on the top of 2D coating hydrogel. Cell culture media can easily penetrate the hydrogel matrix and provide nutrition for long-term cell culture. The growth of cells can be observed easily under microscopy.

TheWell currently provides two products of our hydrogel system: VitroGel 3D (Cat# TWG001, 10 mL/vial) and VitroGel 3D-RGD (Cat# TWG002, 10 mL/vial). VitroGel 3D is the animal origin-free polysaccharide hydrogel which allows the maximum flexibility to manipulate the 3D cell culture environment for different needs. VitroGel 3D-RGD is the hydrogel system modified with GRGDS cell adhesive peptide, promoting the cell attachment and cell-matrix interactions during the 3D cell culture.

Learn more about VitroGel 3D: click here

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