Author Archives: Eryka Bantolino

Prevent Breast Cancer Research Conference 2024

Let’s connect at the very first Prevent Breast Cancer Research Conference 2024 in Manchester, UK! Join us at the first Prevent Breast Cancer Research Conference 2024. Learn about key updates across breast cancer studies and how prediction can change the future of breast cancer diagnoses.  The event will take place on September 24th and 25th […]

miR-34b-5p: A New Hope in Endometrial Cancer Treatment

Institutions:School of Clinical Medicine, Ningxia Medical University Team:Lulu Shi, Dan Yang, Hui Dong, Xueyu Zhang, Caihong Yang Disease Model:3D Cell Models & Functional Assay Subcategory/cell type:Invasion assay/human endometrial cancer AN3CA cells Hydrogel: VitroGel® Hydrogel Matrix Utilizing VitroGel® Hydrogel Matrix to Unveil the Role of miR-34b-5p in Cancer Metastasis Endometrial cancer is a significant health concern, with […]

A Novel Pre-Clinical Model of the Normal Human Breast

Institutions:Manchester Cancer Research Centre, University of Manchester Team:Anthony J. Wilby, Sara Cabral, Nastaran Zoghi, Sacha J. Howell, Gillian Farnie, and Hannah Harrison Disease Model:3D Cell Models & Functional Assay Subcategory / Tissue Type:ex vivo models / human breast tissue Hydrogel:VitroGel® RGD VitroGel® helps to maintain viable organotypic breast tissue cultures over 7 days without losing phenotype properties. Breast cancer remains a significant health challenge, […]

Explant Model of the Normal Human Breast

Introduction Figure 1: Structure of the Normal Human Breast Tissue Following 7 Days in this Culture System. Normal architecture of the human tissue, and the normal bilayer of luminal and basal epithelial cells is maintained. Clinical studies of risk-reducing agents, such as tamoxifen, show a breast cancer risk reduction of at least 38%, and this […]

Tracking Down the Culprit Responsible For AML

Institutions:Jilin University, China Team:Liu, M., Yu, B., Tian, Y., and Li, F. Disease Model:Acute Myeloid Leukemia Hydrogel:VitroGel® RGD A combination of a gene expression network analysis and in vitro assays implicates regulation and modification of a particular enzyme, WTAP, as a source of tumorigenesis in acute myeloid leukemia (AML). One of the several forms of […]

COPD-Linked Extracellular Vesicles Transfer HIF-1α, Fueling Lung Cancer

Institutions:Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy Team:Petraroia, I., Ghidotti, P., Bertolini, G., Pontis, F., Roz, L., Balsamo, M., Suatoni, P., Pastorino, U., Ferretti, A.M., Sozzi, G., & Fortunato, O. Disease Model:Chronic Obstructive Pulmonary Disease (COPD) Hydrogel:VitroGel® 3D   A definitive link between COPD and lung cancer was identified by determining that extracellular vesicles […]

Sartorius and TheWell Bioscience partner to enable more accurate predictions in drug discovery

Göttingen, Germany | April 9, 2024 Collaboration to advance TheWell Bioscience animal-free hydrogel solutions for 3D cell models Solutions address shift from animal-based to more human-relevant organoid models, resulting in more accurate predictions in drug discovery Synergies with Sartorius bioanalytical lab instruments for cell imaging The life science group Sartorius and U.S.-based startup TheWell Bioscience […]