Author Archives: Kyra Baricaua

Game Changer for Lymphoma Therapy Screening

VitroGel® RGD played a key role in preserving tumor architecture for effective drug testing in lymphoma research   Institutions: Swiss Institute for Experimental Cancer Research, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland Team: Albert Santamaria-Martínez, Justine Epiney, Divyanshu Srivastava, Daniele Tavernari, Marco Varrone, Dina Milowich, Igor Letovanec, Thorsten Krueger, Rafael Duran, Giovanni Ciriello, Anne […]

Prolonged Dexamethasone Delivery Using VitroGel® for Protection Against Cisplatin-Induced Ototoxicity

VitroGel® significantly enhanced the delivery of dexamethasone to the inner ear, providing controlled release and improved protection against cisplatin-induced hearing loss.   Institutions:“Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania Team:Maximilian G. Dindelegan, Cristina M. Blebea, Maria Perde-Schrepler, Violeta Necula, Alma A. Maniu, Violeta Pascalau, Catalin Popa, Sergiu Susman, Luciana M. Gherman, Anca D. […]

Harnessing Patient-Derived Organoids to Decode Immunotherapy Responses in Colorectal Cancer

VitroGel® revolutionizes colorectal cancer research by creating a xeno-free platform for patient-derived organoids, enabling groundbreaking insights into tumor-immune interactions and immunotherapy responses.   Institutions:Fondazione Policlinico A. Gemelli IRCCS, Rome Team:Alice Dini, Harlan Carmine Carbone, Annachiara Esposito, Antonio Agostini, Giuseppe Quero, Geny Piro, Lorenzo Priori, Alessia Caggiano, Giulia Scaglione, Alessandra Battaglia, Maria Calegari, Lisa Salvatore, Maria […]

VitroGel® ORGANOID Unlocks Precision High-Throughput Drug Screening Insights in Ovarian Cancer

VitroGel® ORGANOID empowered breakthrough single-cell pharmacotranscriptomic profiling by enabling robust, patient-specific cancer organoid models for drug discovery and resistance analysis.   Institutions: Disease Networks Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland. Team: Alice Dini, Harlan Barker, Emilia Piki, Subodh Sharma, Juuli Raivola, Astrid Murumägi & Daniela Ungureanu. Category: Organoids Subcategory/cell […]

VitroGel® ORGANOID Reveals Unique Pathway Shifts in HOSE Cells Exposed to Tumor Microenvironment

VitroGel® ORGANOID-4 deepened ovarian cancer research by allowing 3D spheroid formation and transcriptomic analysis, identifying key signaling STAT1 and GREM1 activation pathways. Institutions:University of Oulu; Institute for Molecular Medicine Finland; University of Helsinki; Tampere University Hospital and Faculty of Medicine and Health Technology; Okayama University Graduate School of Medicine; Karolinska Institutet. Team:Emilia Piki, Alice Dini, […]

2024 in Review: TheWell Bioscience Milestones, Growth, and Vision for 2025

2024 in Review: TheWell Bioscience Milestones, Growth, and Vision for 2025 We’re excited to celebrate the milestones that defined this remarkable year. We extend our heartfelt gratitude to all the researchers, collaborators, and partners who have supported us in advancing VitroGel® for 3D cell culture, driving innovation in biomedicine and beyond.

TheWell Bioscience 2024 Innovations for Advancing 3D Cell Culture

2024 Innovations for Advancing 3D Cell Culture This year has marked remarkable growth and innovation for TheWell Bioscience. We introduced groundbreaking products, including the VitroGel® Invasion Assay Kits, VitroGel® Starter Kits, VitroPrime Cell Culture Inserts, and VitroPrime Spread-Attach Plate. These innovations further enhance our comprehensive workflow for full lab automation, empowering researchers to achieve greater […]

Targeting System Xc− : A Novel Approach to Inhibit Glioblastoma Invasion

VitroGel® Hydrogel Matrix provided a realistic three-dimensional environment for studying Glioblastoma invasion behavior. Institution:Department of Biological Science, Chungnam National University  Team:Jiyoon Baik, Myunghoon Lee, Jae Hong Yoo, Ahyeon Jo, Kyung-Seok Han Category:3D Cell Models & Functional Assay Subcategory/cell type:Invasion assay/U-87MG Glioblastoma Cells Hydrogel:VitroGel® Hydrogel Matrix (Cat. No: VHM01) Glioblastoma (GBM) is a highly aggressive brain cancer known for its invasive nature, […]