Author Archives: thewellbio

3D Cell Culture of Bone Marrow Stroma Cells (OP9) on VitroGel® Hydrogel System

Application Note TheWell Bioscience Inc. Introduction Mesenchymal stem cells are a type of adult multipotent stem cell that gives rise to bone, cartilage, adipose, and connective tissue. Over the last two decades, they have become a wildly popular potential alternative to embryonic stem cells for regenerative medicine because of their broad plasticity, immunomodulatory, and anti-inflammatory […]

Long-Term Neuron Culture Maturation in 3D Hydrogel Constructs

A comparison study of VitroGel® and Matrigel® for long-term neuron maturation and survival in vitro Comparison Study Martin L. Tomov Stanley Center; Broad Institute of MIT and Harvard Introduction Three-dimensional (3D) tissue cultures have numerous advantages compared to traditional two-dimensional (2D) cultures [1; 5]. Minimizing exposure to hard surfaces can improve cell maturation and survival […]

3D Cell Culture of Human Pancreatic Cancer Cells (PANC-1) on VitroGel® System

Application Note TheWell Bioscience Inc. Introduction 3D culture has become the standard for studying complex systems, such as the tumor microenvironment (TME), in an in vitro setting. These systems allow for insight into the cell-cell interactions and communications that occur in vivo. The use of 3D matrices mimics the complex TME (2) and is even […]

Join us for the Fifth Annual Next Gen Stem Cell Conference

TheWell Bioscience sponsors StemCultures for the Fifth Annual Next Gen Stem Cell Conference on August 3-4, 2017 in Hartford, CT. The meeting is designed for young investigators who will present their work from many different aspects of stem cell research and to build the network of young investigators with graduate students, post-docs and senior investigators […]