Author Archives: thewellbio

Fishing for Therapies for Eye Cancer – Uveal Melanoma

Institutions: Leiden University, The Netherlands; University of Liverpool, UK; & Friedrich-Alexander-Universität, Germany Team: Yin, J., Zhao, G., Kalirai, H., Coupland, S.-E., Jochemsen, A.G., Forn-Cuní, G., Wierenga, A.P.A., Jager, M.J., Snaar-Jagalska, B.E., and Groenewoud, A. Disease Model: Uveal Melanoma Hydrogel: VitroGel® Hydrogel Matrix Zebrafish embryos were tested as a viable model to perform drug screening for […]

Clay is Good to the Bone – Osteoporosis Disease Model

Institutions: King Fahd University, Saudi Arabia; Royal College of Surgeons in Ireland Medical University, Bahrain; and the National University of Computer and Emerging Sciences, Pakistan Team: Abduljauwad, S.N., Habib, T., and ur-Rehman, H. Disease Model: Osteoporosis Hydrogel: VitroGel® 3D The combination of clay microparticles and VitroGel hydrogel appears to promote osteogenesis in human mesenchymal stem […]

Shaking Up Tumors with Sound and Bubbles

Institutions: Cheng Hsin General Hospital and National Taiwan University, Taiwan Team: Chen, K.-W., Hsu, P.-H., Huang, H.-L., Liu, H.-L., Lin, Y.-T., Hsu, C.-Y., Lin, J.-H., and Lin, Y.-H. Disease Model: Gastric Cancer Hydrogel: VitroGel® 3D Antitumor drugs can be delivered to tumors with nanoparticles and microbubbles, and then the uptake of the drugs can be […]

Fighting Pancreatic Cancer – Two Drugs are Better Than One

Institutions: Sungkyunkwan University, South Korea and the University of Oxford Team: Hong, H., Barczak W., Park, S., Heo, J.S., Ooshima, A., Munro, S., Hong, C.P., Park, J., An, H., Park, J.O., Park, S.H., La Thangue, N.B., and Kim, S.-J. Disease Model: Pancreatic Cancer Hydrogel: VitroGel® Hydrogel Matrix A combination therapy of two antitumor drugs shows […]

Mice Recruited to Help Fight Cancer of the Thymus

Institutions: Gifu Graduate School of Medicine, Japan Team: Niwa, R., Hanamatsu Y., Kito, Y., Saigo, C., and Takeuchi, T. Disease Model: Thymic Cancer Hydrogel: VitroGel® Hydrogel Matrix A mouse model of thymic cancer is described, and the results show that viral infection may not always be the cause. In this paper, a team of oncologists […]

Look Ma, No Oxygen! A SCAPs Journey

Institutions: University of Bordeaux, France Team: Mavinga, M., et al. Disease Model: Stem Cell Migration and Bone Regeneration Hydrogel: VitroGel® Hydrogel Matrix Stem cells grown under hypoxic (3% O2) conditions appear to proliferate more rapidly, aiding their maturation into bone or teeth tissue. SCAPs (Stem Cells from Apical Papilla) embedded in VitroGel Hydrogel Matrix and […]

Using Animal-Free VitroGel Hydrogel in Comparison to Animal-based Extracellular Matrix for Xenograft (PDX & CDX) Models

Webinar Abstract: Patient-derived xenografts (PDX) and cell-derived xenografts (CDX) are important tools for studying tumor behavior and drug responsiveness for pre-clinical oncology studies. PDX and CDX models can accelerate the development of new cancer treatments and improve our understanding of tumor biology and efficacy for diverse patients to individualized patients’ specific cancer.   Animal-based extracellular […]

Harvest Organoids/Cells From Animal-Based ECM With VitroGel® Organoid Recovery Solution

Recovering organoids from an animal-based ECM is challenging. Sometimes, the process can take hours using either harsh chemical solutions, strong enzymes, or temperature adjustment, which can damage cells and reduce yield.​   VitroGel® Organoid Recovery Solution is a non-enzymatic cell harvesting solution for quick and efficient recovery of organoids/cells from VitroGel hydrogels or an animal-based […]