Author Archives: thewellbio

Cyclin-dependent kinase 7 (CDK7) Overexpression Implicated as an Independent Predictor of Poor Prognosis of Osteosarcoma

Institution: Department of Orthopedic Surgery at UCLA Team: Hangzhan Ma, Dylan C. Dean, Ran Wei, Francis J. Hornicek and Zhenfeng Duan Application: 3D culture to evaluate the effects of CDK7 in an in vivo environment Disease Model: Osteosarcoma Hydrogel: VitroGel® 3D Osteosarcoma is the most common primary tumor of bone and accounts for 35% of […]

3D Printed Tumor Spheroids for Disease Modeling and Chemotherapeutic Drug Screening

Institution: Florida A&M University Team: Aragaw Gebeyehu1,4, Sunil Kumar Surapaneni1,4, John Huang2, Arindam Mondal1, Vivian Ziwen Wang2, Nana Fatima Haruna2, Arvind Bagde1, Peggy Arthur1, Shallu Kutlehria1, Nil Patel1, Arun K. Rishi3 & Mandip Singh1* Application:  3D bioprint of cancer cell lines to perform drug testings. Cell types: NSCLC-PDX, MDA MB231 WT, and HCC B-27 cells […]

3D Organoid Harvesting

* The video is referencing VitroGel Cell Recovery Solution.  Use VitroGel Organoid Recovery Solution in its place. Recovering organoids from a 3D hydrogel system is challenging. Sometimes, the process can take hours using either harsh chemical solutions, strong enzymes, or temperature adjustment, which can damage cells and reduce yield.​   ​With VitroGel® ORGANOID, recovering organoids […]

2D Coating Culture with VitroGel “Ready-To-Use” Hydrogels

VitroGel® ready-to-use hydrogels simplify the hydrogel 3D cell culture procedure from hours to minutes. Just mix with your cells. There is no crosslinking agent or the need to adjust the hydrogel concentration. The whole 2D coating protocol can be done in 20 minutes (including a 10-15 min waiting time for hydrogel stabilization). The room temperature […]