VitroGel® MSC is a xeno-free (animal origin-free) hydrogel system developed to support three-dimensional (3D) cultures of mesenchymal stem cells (MSCs). The Bead-Droplet method can be used to make hydrogel cell beads for MSC scale-up and long-term culture. This novel culture method generates high-quality MSCs and eliminates the usage of microcarriers for MSC scale-up.
Author Archives: thewellbio
Using the VitroGel Cell Recovery Solution, 3D cultured mesenchymal stem cells (MSCs) can be recovered from hydrogel-cell beads safely and effectively. VitroGel Cell Recovery Solution is enzyme-free and can recover cells in 20 minutes.
Application Note Nana-Fatima Haruna, John Huang TheWell Bioscience, North Brunswick, NJ 08902 Introduction Glioblastoma is the most common primary tumor in the central nervous system. With an incidence of 3–5 out of 100,000 persons in Western countries, glioblastoma is one of the most deadly forms of malignant tumors, which has a median survival time of […]
Application Note Nana-Fatima Haruna, Atsuo Ochi, John Huang TheWell Bioscience, North Brunswick, NJ 08902 Introduction Invasion studies have been crucial in identifying key intracellular signaling pathways and membrane-bound and soluble enzymes that influence cellular movement through a three dimensional (3D) extracellular matrix (ECM)1,2. Such information has been used to investigate mechanisms governing the infiltration of […]
In vitro three-dimensional analysis elucidates the role of cell surface GD3 ganglioside and ST8SIA1 in melanoma brain metastasis. Institution: John Wayne Cancer Institute (JWCI), Fudan University, Providence St. Joseph Health Center, Tel-Aviv University, The University of Texas MD Anderson Cancer Center, Oregon Health and Science University (OHSU) Knight Cancer Institute Portland Team: Romela Irene Ramos, […]
Scientists from Florida A&M University have discovered the ability of Tel and DXTPL combination system to increase the power of DXTPL to penetrate cancer stem cells and decrease the chances of cancer relapse and metastasis. Institution: Florida A&M University Team: Peggy Arthur, Nilkumar Patel, Sunil Kumar Surapaneni, Arindam Mondal, Aragaw Gebeyehu, Arvind Bagde, Shallu Kutlehria, […]
Proud to be recognized as one of the “8 Top 3D Bioprinting Startups in Biotech”. 8 Top 3D Bioprinting Startups Impacting The BioTech Industry
In vitro three-dimensional culture helps to demonstrate that several pseudogenes, including HMGA1P6, are involved in metastasis of ovarian cancer, introducing another unconventional target for cancer therapeutics. Institution: Shandong University Team: Xiaoxue Tian, Jianping Song, Xiyu Zhang, Mingyao Yan, Shourong Wang, Yuqiong Wang, Limei Xu, Ling Zhao, Jian-jun Wei, Changshun Shao, Beihua Kong *, and Zhaojian […]
Maternally derived adipose stem cells have emerged as a possible solution to the common immunological rejection observed in fetal repair surgeries. Institution: Showa University School of Medicine Team: Akihiro Kawashima*, Rika Yasuhara, Ryosuke Akino, Kenji Mishima, Michiko Nasu, Akihiko Sekizawa Application: In vivo utilization of VitroGel RGD to study neuronal differentiation capacity Disease model: Neurometabolic […]
The VitroINK® Mixing Kit was designed to provide a robust mixing of the bioink and cells. Cells can be prepared with VitroINK for a 3:1 mixing ratio using the 3 mL syringe or a 10:1 mixing ratio using the 1 mL syringe. To prepare the bioprinter cartridge, the VitroINK and cell suspension are placed in […]