VitroGel® RGD played a key role in preserving tumor architecture for effective drug testing in lymphoma research Institutions: Swiss Institute for Experimental Cancer Research, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland Team: Albert Santamaria-Martínez, Justine Epiney, Divyanshu Srivastava, Daniele Tavernari, Marco Varrone, Dina Milowich, Igor Letovanec, Thorsten Krueger, Rafael Duran, Giovanni Ciriello, Anne […]
VitroGel® significantly enhanced the delivery of dexamethasone to the inner ear, providing controlled release and improved protection against cisplatin-induced hearing loss. Institutions:“Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania Team:Maximilian G. Dindelegan, Cristina M. Blebea, Maria Perde-Schrepler, Violeta Necula, Alma A. Maniu, Violeta Pascalau, Catalin Popa, Sergiu Susman, Luciana M. Gherman, Anca D. […]
VitroGel® revolutionizes colorectal cancer research by creating a xeno-free platform for patient-derived organoids, enabling groundbreaking insights into tumor-immune interactions and immunotherapy responses. Institutions:Fondazione Policlinico A. Gemelli IRCCS, Rome Team:Alice Dini, Harlan Carmine Carbone, Annachiara Esposito, Antonio Agostini, Giuseppe Quero, Geny Piro, Lorenzo Priori, Alessia Caggiano, Giulia Scaglione, Alessandra Battaglia, Maria Calegari, Lisa Salvatore, Maria […]
VitroGel® ORGANOID empowered breakthrough single-cell pharmacotranscriptomic profiling by enabling robust, patient-specific cancer organoid models for drug discovery and resistance analysis. Institutions: Disease Networks Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland. Team: Alice Dini, Harlan Barker, Emilia Piki, Subodh Sharma, Juuli Raivola, Astrid Murumägi & Daniela Ungureanu. Category: Organoids Subcategory/cell […]
VitroGel® ORGANOID-4 deepened ovarian cancer research by allowing 3D spheroid formation and transcriptomic analysis, identifying key signaling STAT1 and GREM1 activation pathways. Institutions:University of Oulu; Institute for Molecular Medicine Finland; University of Helsinki; Tampere University Hospital and Faculty of Medicine and Health Technology; Okayama University Graduate School of Medicine; Karolinska Institutet. Team:Emilia Piki, Alice Dini, […]
VitroGel® Hydrogel Matrix provided a realistic three-dimensional environment for studying Glioblastoma invasion behavior. Institution:Department of Biological Science, Chungnam National University Team:Jiyoon Baik, Myunghoon Lee, Jae Hong Yoo, Ahyeon Jo, Kyung-Seok Han Category:3D Cell Models & Functional Assay Subcategory/cell type:Invasion assay/U-87MG Glioblastoma Cells Hydrogel:VitroGel® Hydrogel Matrix (Cat. No: VHM01) Glioblastoma (GBM) is a highly aggressive brain cancer known for its invasive nature, […]
VitroGel® Hydrogel Matrix was used to establish mobility, gelatinase activity, protein-protein interaction, and invasion assays to unravel the underlying mechanisms behind the invasiveness of Head and Neck Squamous Cell Carcinoma (HNSCC). Institutions:University of Kansas Medical Center. Departments of Surgery, Biostatistics and Data Science, Otolaryngology and Cancer Biology. Team:Levi Arnold, Marion Yap, Laura Jackson, Michael Barry, […]
Institutions:School of Clinical Medicine, Ningxia Medical University Team:Lulu Shi, Dan Yang, Hui Dong, Xueyu Zhang, Caihong Yang Disease Model:3D Cell Models & Functional Assay Subcategory/cell type:Invasion assay/human endometrial cancer AN3CA cells Hydrogel: VitroGel® Hydrogel Matrix Utilizing VitroGel® Hydrogel Matrix to Unveil the Role of miR-34b-5p in Cancer Metastasis Endometrial cancer is a significant health concern, with […]
Institutions:Manchester Cancer Research Centre, University of Manchester Team:Anthony J. Wilby, Sara Cabral, Nastaran Zoghi, Sacha J. Howell, Gillian Farnie, and Hannah Harrison Disease Model:3D Cell Models & Functional Assay Subcategory / Tissue Type:ex vivo models / human breast tissue Hydrogel:VitroGel® RGD VitroGel® helps to maintain viable organotypic breast tissue cultures over 7 days without losing phenotype properties. Breast cancer remains a significant health challenge, […]
Institutions:Jilin University, China Team:Liu, M., Yu, B., Tian, Y., and Li, F. Disease Model:Acute Myeloid Leukemia Hydrogel:VitroGel® RGD A combination of a gene expression network analysis and in vitro assays implicates regulation and modification of a particular enzyme, WTAP, as a source of tumorigenesis in acute myeloid leukemia (AML). One of the several forms of […]
