VitroGel® ORGANOID-4 deepened ovarian cancer research by allowing 3D spheroid formation and transcriptomic analysis, identifying key signaling STAT1 and GREM1 activation pathways. Institutions:University of Oulu; Institute for Molecular Medicine Finland; University of Helsinki; Tampere University Hospital and Faculty of Medicine and Health Technology; Okayama University Graduate School of Medicine; Karolinska Institutet. Team:Emilia Piki, Alice Dini, […]
VitroGel® Hydrogel Matrix provided a realistic three-dimensional environment for studying Glioblastoma invasion behavior. Institution:Department of Biological Science, Chungnam National University Team:Jiyoon Baik, Myunghoon Lee, Jae Hong Yoo, Ahyeon Jo, Kyung-Seok Han Category:3D Cell Models & Functional Assay Subcategory/cell type:Invasion assay/U-87MG Glioblastoma Cells Hydrogel:VitroGel® Hydrogel Matrix (Cat. No: VHM01) Glioblastoma (GBM) is a highly aggressive brain cancer known for its invasive nature, […]
VitroGel® Hydrogel Matrix was used to establish mobility, gelatinase activity, protein-protein interaction, and invasion assays to unravel the underlying mechanisms behind the invasiveness of Head and Neck Squamous Cell Carcinoma (HNSCC). Hydrogel:VitroGel® Hydrogel Matrix (Cat. No: VHM01) Head and neck squamous cell carcinoma (HNSCC) poses a significant global health challenge due to its high incidence […]
Institutions:School of Clinical Medicine, Ningxia Medical University Team:Lulu Shi, Dan Yang, Hui Dong, Xueyu Zhang, Caihong Yang Disease Model:3D Cell Models & Functional Assay Subcategory/cell type:Invasion assay/human endometrial cancer AN3CA cells Hydrogel: VitroGel® Hydrogel Matrix Utilizing VitroGel® Hydrogel Matrix to Unveil the Role of miR-34b-5p in Cancer Metastasis Endometrial cancer is a significant health concern, with […]
Institutions:Manchester Cancer Research Centre, University of Manchester Team:Anthony J. Wilby, Sara Cabral, Nastaran Zoghi, Sacha J. Howell, Gillian Farnie, and Hannah Harrison Disease Model:3D Cell Models & Functional Assay Subcategory / Tissue Type:ex vivo models / human breast tissue Hydrogel:VitroGel® RGD VitroGel® helps to maintain viable organotypic breast tissue cultures over 7 days without losing phenotype properties. Breast cancer remains a significant health challenge, […]
Institutions:Jilin University, China Team:Liu, M., Yu, B., Tian, Y., and Li, F. Disease Model:Acute Myeloid Leukemia Hydrogel:VitroGel® RGD A combination of a gene expression network analysis and in vitro assays implicates regulation and modification of a particular enzyme, WTAP, as a source of tumorigenesis in acute myeloid leukemia (AML). One of the several forms of […]
Institutions:Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy Team:Petraroia, I., Ghidotti, P., Bertolini, G., Pontis, F., Roz, L., Balsamo, M., Suatoni, P., Pastorino, U., Ferretti, A.M., Sozzi, G., & Fortunato, O. Disease Model:Chronic Obstructive Pulmonary Disease (COPD) Hydrogel:VitroGel® 3D A definitive link between COPD and lung cancer was identified by determining that extracellular vesicles […]
Institutions:The BioRobotics Institute and Department of Excellence in Robotics & AI, Scuola Superiore Sant’Anna, Pisa, Italy; and several other European institutions Team:Ricotti, L., Cafarelli, A., Manferdini, C., et al. & Lisignoli, G. Disease Model:Bone Tissue Regeneration Hydrogel:VitroGel® RGD In vitro assays with cells embedded in VitroGel RGD demonstrate that ultrasound waves can be used to […]
Institutions: Translational Oncology Research Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.; and several other Italian institutions Team: Méndez, A.B.D., Sacconi, A., Tremante, E., et al. & Rizzo, M.G. Disease Model: Brain Cancer Hydrogel: Cyto3D® Live-Dead Assay Kit Three micro RNA species have been identified that are correlated with poor outcomes in glioma patients. […]
Institutions: University Hospital Regensburg, Germany Team: Babl, N., Hofbauer, J., Matos, C., Voll, F., Menevse, A.N., Rechenmacher, M., Mair, R., Beckhove, P., Herr, W., Siska, P.J., Renner, K., Kreutz, M., & Schnell, A. Disease Model: Colorectal Cancer Biomarker: Cyto3D® Live-Dead Assay Kit Cholesterol, in the form of LDL, demonstrates an intriguing ability to stimulate the […]
