We are excited to attend again this year’s AACR 2024 (American Association of Cancer Research) in San Diego, California, hosted at the San Diego Convention Center. Please stop by booth #4131 to speak with our team members about how our VitroGel® family of animal-free hydrogels can replace animal-derived ECM for your 3D cell culture research. […]
Key Takeaways: Normal breast tissue can be cultured for 7 days with no changes in proliferation or viability. Tissue maintains expression of oestrogen and progesterone receptors and remains responsive to hormones. Using this model, we aim to identify mechanisms of resistance to preventative agents and screen for novel approaches to breast cancer risk-reduction that could […]
Institutions:The BioRobotics Institute and Department of Excellence in Robotics & AI, Scuola Superiore Sant’Anna, Pisa, Italy; and several other European institutions Team:Ricotti, L., Cafarelli, A., Manferdini, C., et al. & Lisignoli, G. Disease Model:Bone Tissue Regeneration Hydrogel:VitroGel® RGD In vitro assays with cells embedded in VitroGel RGD demonstrate that ultrasound waves can be used to […]
Institutions: Translational Oncology Research Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.; and several other Italian institutions Team: Méndez, A.B.D., Sacconi, A., Tremante, E., et al. & Rizzo, M.G. Disease Model: Brain Cancer Hydrogel: Cyto3D® Live-Dead Assay Kit Three micro RNA species have been identified that are correlated with poor outcomes in glioma patients. […]
Introduction Contemporary hydrogel matrices provide enormous advantages for two- and three-dimensional cell culturing. They provide an environment that mimics that of natural tissue, increasing growth rates and offering conditions in which native in vivo cell behavior can be reliably assayed. Choices for hydrogel matrices include those from animal-based extracellular matrices (ECMs) such as Matrigel and […]
Introduction In vitro intestinal models serve as vital tools for studying biological processes, drug absorption and cytotoxicity while reducing the need for animal testing. Typically, these models consist of enterocytes and mucus-producing cells that are cultured for three weeks and closely mimic the human epithelium. Key components also include the extracellular matrix (ECM) for structural […]
Institutions: University Hospital Regensburg, Germany Team: Babl, N., Hofbauer, J., Matos, C., Voll, F., Menevse, A.N., Rechenmacher, M., Mair, R., Beckhove, P., Herr, W., Siska, P.J., Renner, K., Kreutz, M., & Schnell, A. Disease Model: Colorectal Cancer Biomarker: Cyto3D® Live-Dead Assay Kit Cholesterol, in the form of LDL, demonstrates an intriguing ability to stimulate the […]
Institutions:Korea Advanced Institute of Science and Technology Team:Beha, M.J., Kim, J.-C., Im, S.H., Kim, Y., Yang, S., Lee, J., Nam, Y.R., Lee, H., Park, H.-S., & Chung, H.J. Disease Model:Breast Cancer Hydrogel:VitroGel® Hydrogel Matrix Anticancer drugs were combined with CRISPR/Cas9 gene editing complex in a powerful nanoparticle structure that shows promise in targeting tumor cells […]
Dr. Alejandra Ferrer Díaz earned her doctorate from Rutgers University, where she studied the interactions between mesenchymal stem cells and breast cancer cells in the bone marrow microenvironment. She is a research scientist at TheWell Bioscience, primarily focusing on developing and refining cell-based assays and co-culture models using the VitroGel hydrogel system. Webinar Summary: Advanced […]
Institutions:City of Hope National Medical Center, CA Team:Omori, K., Qi, M., Salgado, M., et al., and Kandeel, F. Disease Model:Diabetes & Kidney Transplantation Hydrogel:VitroGel® 3D Human islet beta cells can be grown in 3D cell culture for up to eight weeks, rather than the three days they would survive in standard 2D culture. These cells […]
