Application Note Bhavya Shah, John Huang TheWell Bioscience, North Brunswick, NJ 08902 Introduction Despite recent progression, the need for reliable, repeatable in vitro three-dimensional (3D) tissue culture human skin models exist to further understand the mechanisms behind various pathologies related to the skin and/or dermal fibroblasts1-3. Such 3D models are increasingly important as two-dimensional (2D) […]
Application Note Nana-Fatima Haruna, Bhavya Shah,John HuangTheWell Bioscience, North Brunswick, NJ 08902 Introduction There is an increasing need for the generation of data that accurately reflects the biological systems of patients 1-3. To achieve this goal, researchers need to study disease models in microenvironments that depict the complex human extracellular matrix and support the comprehensive […]
We are excited that our VitroGel®, a xeno-free hydrogel system, is part of the National Institute of Standards and Technology’s (NIST) goal to establish a standard for measuring cell viability in manufactured tissues. For more information on the project visit https://www.nist.gov/mml/bbd/biomaterials/measuring-cell-viability-scaffolds
Institution: Precision Medicine Research Center, Seoul National University Team: Pang, K., Park, J., Ahn, S. G., Lee, J., Park, Y., Ooshima, A., Mizuno, S., Yamashita, S., Park, K.-S., Lee, S.-Y., Jeong, J., Ushijima, T., Yang, K.-M., & Kim, S.-J. Application: Targeting Vimentin to suppress metastasis breast cancer Disease Model: Breast Cancer Hydrogel: VitroGel® 3D Among […]
Institution: Cancer Center at the First Hospital of Jilin University Team: Qiliang Yin, Na Xu, Dongsheng Xu , Mingxin Dong, Xiumin Shi, Yan Wang, Zhuo Hao, Shuangshuang Zhu, Donghai Zhao, Haofan Jin, and Wensen Liu Application: In vitro models of adipose-derived mesenchymal stem cells Disease Model: Adipose-derived mesenchymal stem cells (ADMSCs) Hydrogel: VitroGel® RGD In recent […]
Institution: The First Affiliated Hospital of Zhengzhou University David Geffen School of Medicine at UCLA Team: Wenlong Feng, Dylan C. Dean, Francis J. Hornicek, Jinglu Wang, Yanyan Jia, Zhenfeng Duan, and Huirong Shi Application: Studying the relationship of ATR and p-ATR in 3D ovarian cancer models Disease Model: Ovarian Cancer Cell Lines Hydrogel: VitroGel® 3D […]
Institution: Xiamen Medical College Team: Tianshu Lan, Jingyi Guo, Xiaoming Bai, Zengjiong Huang, Zhimin Wei, Guicheng Du, GuoliangYan, Lebin Weng, Xue Yi Application: Development of 3D islet pancreatic beta-cells (β-cells) Disease Model: The mouse β islet cell line, β-TC-6 Hydrogels: VitroGel® RGD, VitroGel® 3D, VitroGel® Cell Recovery Solution Islet transplantation is currently the only firmly […]
Institution: Fujian Medical University Team: Chaoyu Zhang, Ting Wang, Li Zhang, Penghong Chen, Shijie Tang, Aizhen Chen, Ming Li, Guohao Peng, Hangqi Gao, Haiyan Weng, Haoruo Zhang, Shirong Li, Jinghua Chen, Liangwan Chen, Xiaosong Chen Application: Developing ADSCC-CM and VitroGel hydrogel complex to study hypertrophic scar prophylaxis Disease Model: Adipose-derived stem cells Hydrogel: VitroGel® RGD […]
Institution: Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou Team: Haoyue Xu, Yuhan Han, Gang Zhao, Long Zhang, Zongren Zhao, Zhen Wang, Liang Zhao, Lei Hua, Konduru Naveena, Jun Lu, Rutong Yu, and Hongmei Liu Application: Testing Lipid Polymer nanoparticle (LN) on in vivo and in vitro glioblastoma models. Disease Model: Glioblastoma Hydrogel: VitroGel® […]
Application Note Nana-Fatima Haruna, Bhavya Shah, John Huang TheWell Bioscience, North Brunswick, NJ 08902 Introduction Cancer is a very meticulous disease that involves heterogeneous solid tumors subjected to complex extracellular conditions. These conditions, such as hypoxia and extracellular compositions, contribute to the pathogenesis of the disease. The functional activity and gene expression patterns of the […]
